Sheldon: *knock knock knock* Dr. Wolcott? *knock knock knock* Dr. Wolcott? *knock knock knock* Dr. Wolcott? [sound of many locks clacking]
Howard: That's a lot of locks.
Leonard: Mm. That was a lot of knocks, they were made for each other.

Raj: Here you go. I've got everything well need for the big game. Low fat turkey jerky, low-carb beer, 100-calorie snack packs.
Leonard: You pick up a Y chromosome while you were there? You might be short one.

Leonard: My mother's texting you?
Penny: Yeah. We've been talking a lot lately.
Leonard: Why? She sick of talking to the magic mirror on the wall?

Penny: Where's Sheldon?
Leonard: Oh, he was up late last night, so I gave him an early dinner and put him to bed.
Bernadette: That's so sweet.
Leonard: Yeah, but now he's gonna be up at dawn and want to play.

Sheldon: Now, Penny, we don't consume alcohol during Dungeons and Dragons. It impairs our judgment.
Penny: Oh, this isn't alcohol. It's a magic potion that makes me like you.
Leonard: Double potion, please.

Leonard: Hypothetically, if I had access to a lieutenant Uhura uniform, would you wear it?
Priya: Leonard, it is a source of great pain to me and my family that my brother has that outfit in his wardrobe.

Leonard: Listen, Sheldon, this is stupid. I don't see why we can't be friends. And I'm willing to drive you around and help you out with stuff. I just don't want to do it because of some silly roommate agreement.
Sheldon: What are you proposing?
Leonard: That we go back to the way things were. But when I do something for you, you show a little appreciation.
Sheldon: And how would I do that?
Leonard: You say thank you.
Sheldon: Every time?
Leonard: It's not crazy.

Howard: That was weird, right?
Leonard: Was it? I honestly can't tell anymore.

Beverly Hofstadter: Penny, I hope the example of my failed marriage to Leonard's father doesn't discourage you from the commitment you've made to one another.
Penny: No, of course not.
Beverly Hofstadter: Although Alfred and I had a lot more going for us than you two.
Leonard: Mom, please save something for the toast.

Priya: It's a little weird your ex-girlfriend hanging out here all the time.
Leonard: I know. I usually never see my ex-girlfriends, unless their hard drives crash.

Leonard: You see, I used to be a jackass, but I stopped myself. I became a good guy. See, that's kind of my superpower. I'm like Captain Good Guy!
(Alice pushes him out, then slams door)
Leonard: It's okay. Did the right thing. *tightens his jacket* You idiot!

Leonard: [answering the phone] Hello. Hey. It's Howard. Oh, us, too.
Penny: Wait, what?
Leonard: They're gonna stay. The kids are fine. Bernie's parents took over. Really? Oh, poor little guy.
Penny: Is Michael okay?
Leonard: Yeah, it's Stuart. Bernie's dad gave him a hug, cracked a rib.

Leonard: I got all your favorites. Beer, wings, sliders. We can watch the football game. I even painted my stomach.
Penny: Go Sports?
Leonard: Well, in case you were in the mood for baseball, I didn't want to look ridiculous.

Amy: I'm in this relationship, too. I need to stand up for myself.
Leonard: Of course you do.
Amy: And if he doesn't like it, he can move back here.
Leonard: Oh, he can try. He'd just need a good locksmith.

Guy: Is this guy for real?
Leonard: Boy, I wish I could say no.