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Quote from the episode The Commitment Determination

Sheldon: Amy's mad at me, and I'm not clear why.
Penny: Okay, were you talking before she got upset?
Sheldon: Yes.
Penny: That's probably it.

Quote from the episode The Earworm Reverberation

Penny: So you have a song stuck in your head. It happens to everybody.
Sheldon: Well, I'm not everybody. I have an eidetic memory. I should be able to remember what song this is, but I can't. Something's wrong with me.
Penny: I told you if we were patient, he'd figure it out for himself.

Quote from the episode The Prom Equivalency

Penny: What kind of teenager did you think I was?
Bernadette: Slutty.
Amy: Easy.
Penny: The word is 'popular'.

Quote from the episode The Bachelor Party Corrosion

Penny: What are you doing back?
Leonard: We got a flat and couldn't get the tire off.
Penny: Oh, I'm sorry.
Leonard: Thank you.
Penny: If it makes you feel any better, I pierced Amy's ears and her mom made her sit in my closet.
Sheldon: We blew up Feynman's van.
Penny: My dad killed my pig with his tractor.
Leonard: I spent the night in Mexico with Sheldon.
Penny: You win.

Quote from the episode The Discovery Dissipation

Penny: (To Raj's dog) Bark once if you need me to call PETA.

Quote from the episode The Leftover Thermalization

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Quote from the episode The Champagne Reflection

Dan: Well one thing I've been meaning to tell you, is that the company's gonna stop paying for our coffee.
Bernadette: No problem. When does that start?
Dan: Five months ago.
Bernadette: What? Who's been paying for my coffee.
Dan: All of us.
Penny: Yep, it comes from the swear jar we put money in when you curse.

Quote from the episode The Cooper Extraction

Raj: (To Amy) If you were having Sheldon's baby, would you really want him in the room?
Penny: Yeah, if he's in the room when they're making the baby, I'll give you $10.

Quote from the episode The Anything Can Happen Recurrence

Penny: Sheldon, what did we say about being a nicer friend?
Leonard: Thank you.
Penny: Leonard, what did we say about being a gullible weeny?

Quote from the episode The Comic Book Store Regeneration

Sheldon: Is that all you have? Shop-worn tidbits like "talk to her" and "let it go"? Gee, Penny, life's given me lemons, what should I do?
Penny: Well, you could shove them somewhere.

Quote from the episode The Panty Pinata Polarization

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Quote from the episode The Colonization Application

Penny: Come on, we are not old, boring people. We can do better than this.
Leonard: That's true. How late did we stay up last night?
Penny: Almost 1 am.
Leonard: Damn straight almost 1 am. And we weren't even watching TV, we were watching Netflix like the kids do.
Penny: Yeah. Is it a comedy, is it a drama? Nobody knows!

Quote from the episode The Status Quo Combustion

Penny: No, mom. It's the same guy I've been going out with for the past two years. Yeah, the scientist. Well, it's complicated. He works with lasers and atomic magnets. No, I did not see it coming. No, we have not set a date. No, I am not pregnant. Yeah, this is a first for our family.

Quote from the episode The Commitment Determination

Leonard: What am I supposed to do?
Penny: Err, keep your mouth off other women.

Quote from the episode The Itchy Brain Simulation

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

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