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Quote from Sheldon in the episode The Middle-Earth Paradigm

Leonard: What's this?
Sheldon: Tea. it's costumary to serve hot beverages when one is in emotional distress. [pats Leonard's head] There there. You want to talk about it?
Leonard: No.
Sheldon: Thank godness. 'There there' was really all I had.

Quote from Sheldon in the episode The Middle-Earth Paradigm

Leonard: What's that?
Sheldon: Tea. When people are upset the cultural convention is to bring them hot beverages. (Sheldon stiffly pats Leonard twice on the shoulder.)There, there. You wanna talk about it?
Leonard: No.
Sheldon: Good. 'There there' was really all I had.

Quote from Leonard in the episode The Middle-Earth Paradigm

Leonard: There's not going to be a confrontation. I bet he can't even spell confrontation.
Kurt: C-O-N...frontation.

Quote from Sheldon in the episode The Middle-Earth Paradigm

Sheldon: You know, we were annihilated by our own incompetence and the inability of some people to follow the chain of command.
Leonard: Sheldon, let it go.
Sheldon: No, I want to talk about the fact that Wolowitz shot me in the back.

Quote from Penny in the episode The Hamburger Postulate

Sheldon: I need your help in a matter of semiotics.
Penny: What?
Sheldon: Semiotics, the study of signs and symbols as a branch of the philosophy related to linguistics.
Penny: Okay, honey, I know you think you are explaining yourself, but you're really not.

Quote from Sheldon in the episode The Hamburger Postulate

Sheldon: Can't we just go to Big Boy? They only have one burger: the Big Boy.
Penny: The Barbecue Burger is like the Big Boy.
Sheldon: Excuse me, in a world that already includes a Big Boy, why would I settle for something that's like a Big Boy?

Quote from Penny in the episode The Hamburger Postulate

Sheldon: Who do I speak to about permanently reserving this table?
Penny: I don't know, a psychiatrist?

Quote from Leslie Winkle in the episode The Hamburger Postulate

Leslie: Come for the breasts, stay for the brains!

Quote from Leslie Winkle in the episode The Hamburger Postulate

Leslie: Oh, Leonard, you magnificent beast.

Quote from Leslie Winkle in the episode The Hamburger Postulate

Leslie: Listen Leonard, neither of us are neuro-scientists, but we both understand the bio-chemistry of sex, ... I mean: Dopamine in our brain is released across synapses causing pleasure. You stick electrodes in a rat's brain, give him an orgasm button and he'll push that thing 'till he starves to death.
Leonard: Who wouldn't?

Quote from Sheldon in the episode The Hamburger Postulate

Sheldon: Waitresses don't yell at you at Big Boy.

Quote from Sheldon in the episode The Hamburger Postulate

Leslie: I didn't know you eat here.
Sheldon: We don't, this is a disturbing aberration.

Quote from Howard in the episode The Hamburger Postulate

Leonard: Leslie, this is Penny, she lives across the hall from Sheldon and me.
Howard: ... And walks in quiet beauty like the night.
Penny: Howard, I asked you not to do that.

Quote from Sheldon in the episode The Hamburger Postulate

Sheldon: My equations, someone's tampered with my equations.
Leonard: Are you sure?
Sheldon: Of course I'm sure. Look at the beta function of quantum chromodynamics. The sign's been changed.
Leonard: Oh, yeah. But doesn't that fix the problem you've been having?
Sheldon: Are you insane? Are you out of your mind? (looking at board) Are you--? Hey, look, that fixes the problem I've been having.

Quote from Leonard in the episode The Hamburger Postulate

Leonard: If Penny didn't know that Leslie had already turned me down then that would unambiguously mean that she, Penny, thought I should ask her, Leslie, out, indicating that she, Penny, had no interest in me asking her, Penny, out but because she did know that I had asked Leslie out and that she, Leslie, had turned me down then she, Penny, could be offering me consolation. "That's too bad, you would have made a cute couple" but while thinking "good, Leonard remains available."
Sheldon: You're a lucky man Leonard.
Leonard: How so?
Sheldon: You're talking to one of three men in the western hemisphere capable of following that train of thought.
Leonard: Well, what do you think?
Sheldon: I said I could follow it, I didn't say I cared.

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