Raj: Well, I can't eat like a ten-year-old all the time.
Penny: You're dating somebody! Who is it?
Raj: What? What are you talking about?
Penny: You only watch what you eat when you're afraid you might have to take your shirt off.

Amy: Do you think it's possible you might enjoy being on your own for a little while?
Sheldon: It's hard to say. I've never really lived by myself. What if I become strange and eccentric?
Amy: I'll love you no matter what.
Sheldon: Howard Hughes saved his urine in milk bottles.
Amy: We'll cross that bridge when we come to it.

Leonard: He really worked with the Drug Enforcement Agency?
Penny: He didn't know it 'til he was cuffed, but yeah.

Raj: What's the worst that could come of this meeting?
Howard: I don't know. They take the invention away, and I get nothing?
Raj: Okay, that's not so bad. You know what happened to the scientists that worked on the Manhattan Project? The government forced them to move to the desert. They had to live in secret, and when Oppenheimer objected to what they made him do, they destroyed his reputation.
Howard: What's the point of that story?
Raj: I just read a book about Oppenheimer, seemed like a chance to show off.

Sheldon: Stuart, wait. I do know what it feels like to be left out.
Bert: I know how it feels, too.
Sheldon: All right, this is about me and him; you're not part of it.

Sheldon: We seem to be moving on to the annual coitus portion of your birthday festivities.
Amy: Is that okay?
Sheldon: I didn't put on my come-hither plaid PJs for nothing.

Amy: Sheldon, your mother's an attractive woman. You need to get used to the fact that men are going to be interest in her.
Sheldon: Well, and you need to drive the car and mind your business.
Amy: I will not have you be disrespectful to me.
Sheldon: What- you're not my mother.
Mary Cooper: Don't you be disrespectful to her.
Sheldon: Yes ma'am.
Mary Cooper: You'll get there. You've just gotta put some zing on it.

Penny: You want food?
Bernadette: Yeah, breastfeeding burns, like, 5,000 calories a day. (To Amy) Do not touch that phone!

Sheldon: Being with Amy has awoken the sexual creature within. When I see a pretty gal walking down the street, I think, "hubba hubba" like any other guy.
Penny: You kiss your mother with that mouth? 'Cause it's fine.

Howard: You know, maybe before our meeting we should talk to a lawyer.
Leonard: That's not a bad idea.
Raj: Well, you must have someone in your family that's a lawyer.
Howard: Why? Because I'm Jewish? That's like me saying, "Hey, you're Indian. Doesn't your cousin work in a call center?"
Raj: My cousin does work in a call center.
Howard: And my cousin's a lawyer.

Penny: You know, when Leonard's feeling anxious, I make him take a long walk.
Amy: Does that help?
Penny: For a while, then he comes back.

Leonard: Sheldon, this is not a big deal. It's a little white lie, everyone does it.
Raj: Not me, I'm a 100% honest in all of my relationships.
Howard: And how single are you right now?
Raj: Eating-cake-on-the-toilet single.

Susan: Penny, I don't know what I was worried about. Your friends are just lovely.
Penny: Oh, thanks, Mom.
Susan: Although that Sheldon is a bit peculiar.
Penny: Is he? I never noticed.
Wyatt: He reminds me of that turkey we had who drowned looking up at the rain.

Sheldon: I admire you, Leonard.
Leonard: Really, why?
Sheldon: You're happy with who you are. You don't get jealous of other people. Instead of being weighed down by ambition, you just float along like a dead body in a river.
Leonard: I couldn't just take the compliment. I had to ask why.

Amy: All right, you can open your eyes. I thought I'd let Harry Potter make things hotter.