Amy: Whose bra is this?
Sheldon: It's not yours? Oh, my. How embarrassing for both of us.
Amy: It's Penny's.
Sheldon: Hey. You broke up with me, it's none of your business whose naked bosom I'm smushing around like pizza dough.

Penny: I think it's so adorable you're making Sheldon breakfast.
Leonard: Well, he's having a rough time. Amy broke his heart, the DVR cut off the last minute of Doctor Who, that crow followed him home.

Stuart: Anyone else need anything before I go?
Howard: I'll give you a dollar if you make fun of Raj.
Stuart: That's mean.
Howard: Five.
Stuart: You look like Tigger if Tigger looked like a jackass.
Howard: Uh, if you ever need a reference or anything, just let me know.

Alfred Hofstadter: Well, on that note, there are many cultures that have an apocalyptic flood as part of their mythology.
Mary Cooper: I don't have a mythology. I have the unerring Word of God. But that's very interesting.
Alfred Hofstadter: Oh. I, I didn't mean to disparage your faith. Actually, I admire it.
Mary Cooper: Really?
Alfred Hofstadter: Yes. Yes, I'm an agnostic myself. But I have prayed many times to God, to turn my wife into a pillar of salt.
Mary Cooper: Well, He came close. Turned her into a giant block of ice.

Sheldon: I understand that we are no longer a couple, but I'd like to remind you that we made a baby together.
Amy: What baby?
Sheldon: A precocious, little Internet show known as Fun with Flags.

Amy: Are you hungry? How about that sushi place you love?
Bernadette: Doctor said I can't have sushi.
Penny: Okay, look, we don't have to go anywhere. We can just, you know, stay here and hang out in the hot tub.
Bernadette: Doctor said I can't go in the hot tub.
Amy: Maybe you should get a new doctor. What, he said you can't laugh either?

Sheldon: You're kidding! What kind of maniacs have coitus in someone else's bedroom?!
Howard: Thank you, Pasadena! Good night!

Amy: Sheldon, what's wrong?
Sheldon: I wanted to let you know I'll be spending your birthday with you.
Amy: Okay.
Sheldon: See, I had tickets to the Star Wars premiere that night, but Professor Proton came to me in a dream, dressed as Obi-Wan Kenobi, and convinced me that I should be with you.
Amy: Obi-what?
Sheldon: I'll let you get back to sleep now. Good night.
Amy: Good night. Uh, Sheldon, were you actually not going to spend my birthday with me?
Sheldon: (feigning sleepiness) It's late, gotta go, bye.

Sheldon: And then the Czech Republic says to Slovakia, I don't think you understand how being broken up works.
Can you believe that? You'd think the Czech Republic would try to hold on to what it did, given it's not as young as it used to be. And I don't see any other countries lining up to invade its southern borders.

Sheldon: Your friends? I think you mean my friends. And why wasn't I invited to this?
Amy: Maybe because the two of us being there would make them feel awkward.
Sheldon: We make everyone feel awkward. That's our thing!

Leonard: I love you.
Penny: Who cares?

Howard: May I say something?
Bernadette: Is it about how I can't have new wallpaper 'cause your dad left when you were little and your mom died?
Howard: Never mind.

Raj: You're not wrong about Fruit Stripe. I-I was always a Hubba Bubba man.
Howard: Hubba Bubba over Dubble Bubble? You're crazy.
Raj: Hey, the jaw wants what it wants.

Moviegoer: Star Trek stinks!
Wil Wheaton: Yeah? Live long and suck it!

Leslie Winkle: Uh, in the past, I would've said something obnoxious, like, "Happy birthday, dumbass". But I'm not gonna do it. You and I have both grown a lot, and it's just so nice to see you all again. So happy birthday, Sheldon.
Sheldon: Oh. Oh, now, you know I hate change. Say it.
Leslie Winkle: Happy birthday, dumbass!