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Quote from Leonard in the episode The Mommy Observation

Amy: Should you really be sitting in Sheldon's spot?
Raj: He's in Texas, he'll never know.
Penny: Wouldn't be so sure about that.
Leonard: Yeah, he has a very sensitive butt. Look, it's true. Once I saw him sit on a bunch of loose change and add it up.

Quote from Penny in the episode The Mommy Observation

Penny: Ooh, I'm going to check the fridge and see if there are any clues inside a beer.

Quote from Sheldon in the episode The Proton Displacement

Sheldon: As it happens, I'm also spending the day with a beloved children's science personality. Isn't that right, new friend and colleague Bill Nye, the Science Guy?
Sheldon: Sorry, I replaced you with a newer model.

Quote from Sheldon in the episode The Pulled Groin Extrapolation

Amy: I need someone to accompany me to the wedding of Dr. Moranelli and Dr. Gustafson this Friday. They're kind of the Brad and Angelina of the primatology department.
Leonard: Wouldn't you rather bring Sheldon?
Amy: I would, but the last wedding we went to was a disaster. He behaved like a child the entire time.
Sheldon: Not my fault. You said there'd be other scientists there my age.

Quote from Sheldon in the episode The Gothowitz Deviation

Sheldon: There are more things in Heaven and Earth, Horatio, than are dreamt of in your philosophy.

Quote from Sheldon in the episode The Raiders Minimization

Sheldon: If I'd known this was about time travel, I'd have watched this much sooner.

Quote from Sheldon in the episode The Junior Professor Solution

Sheldon: I'm sensing awkwardness. Am I right?
Amy: Yes.
Sheldon: Swish.

Quote from Sheldon in the episode The Locomotion Interruption

Sheldon: No, I'm not okay. I'm wearing borrowed pants, I don't have ID, and one of the officers here won't stop calling me chicken legs.

Quote from Bernadette in the episode The Gorilla Dissolution

Bernadette: Almost there. You're doing great.
Howard: Thanks for lifting my spirits. Next time, try lifting the box.

Quote from Penny in the episode The Mommy Observation

Penny: If you do something cool in science, you might change the world. If I become a famous actress ... I'm not going to tell you why movie stars are the best, they just are.

Quote from Sheldon in the episode The Friendship Turbulence

Sheldon: Oh apple juice stay where you are.

Quote from Sheldon in the episode The Terminator Decoupling

Sheldon: Leonard, let me tell you something. Personal robots cannot get here soon enough.

Quote from Raj in the episode The Positive Negative Reaction

Raj: Groundbreaking revelations, tropical drinks. Tell me this isn't like the best episode of Sex and the City.

Quote from Bernadette in the episode The Positive Negative Reaction

Bernadette: We were out one night, and things got a little spontaneous.
Amy: Oh, that sounds juicy.
Bernadette: Well, Sheldon was going on and on about time zones and railroad schedules, and I went out-
Penny: Wait, I remember that. Hang on. You did it at our place?
Bernadette: Kind of on Sheldon's bed.
Amy: What?!
Penny: No!
Bernadette: I was headed to the bathroom, and I passed Howie on his way out. Usually he says, "Do not go in there," but this time he said, "Hey, let's go in here."

Quote from Penny in the episode The Sales Call Sublimation

Leonard: Hi.
Penny: Hey, how'd it go?
Leonard: Oh, great. Dr. Gallo is terrific. You know, I-I've always been insecure that no one cares about what I have to say, but she made me see-
Penny: Yeah, no one cares. Did you help me out or not?

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