Amy: You were right. I had nothing to worry about. That skank's your problem, not mine.

Amy: Look at you, putting on a brave face.
Penny: There's nothing to be brave about. Everything's fine.
Amy: Really? I don't know how much you know about primate behavior, but Sheldon's assistant was clearly courting Leonard. Were she a mandrill, she would have bent over and displayed her brightly colored hindquarters like a big red welcome mat. By the way, you try that at the junior prom, you get kicked out.

Amy: What's up?
Leonard: Penny's been talking to my mother like they're best friends, and it's kind of freaking me out.
Amy: Okay I'm pretty sure they're not best friends. 'Cause you can only have one best friend. And Penny has that, and (clicks tongue) it's me.

Sheldon: See, he gets Ewoks in his bed.
Amy: You've got Chewbacca. That's enough.

Amy: So, listen, Sheldon, I was thinking, since this is gonna be our first Halloween party as boyfriend and girlfriend, I thought it might be fun for us to go in a couples costume.
Sheldon: I couldn't agree more.
Amy: Really? I find that inconsistent with everything I know about you.

Sheldon: What if we were to go as dinner table favourites salt and pepper?
Amy: You know salt makes me retain water and my cousin William was ground to death in a pepper factory accident.

Penny: I remember telling Jenny Runyon that I would teach her how to flirt with boys if she put my name on her project. I got an "A", she got pregnant.
Amy: Girls like you are why I had to come straight home after school.

Amy: Penny and I have the same "You're crazy" look? That's kind of sweet.

Penny: Maybe I should just move back to Nebraska.
Amy: No, I can't let you do that.
Penny: Why not?
Amy: For the first time ever, I have a thriving social life. And no pressure, but it kind of lives and dies with you.

Sheldon: How can you sleep? I'm not done making you feel better. I still have to put a cold rag on your head, sing to you and apply VapoRub to your chest.
Amy: You, you want to rub something on my chest?
Sheldon: Yes. All over it.
Amy: Maybe we should start with that.
Sheldon: Now you're being a responsible patient. Now, you may notice some tingling.
Amy: Oh, I'm counting on it.

Sheldon: So you're not going to do something just because you think it might upset me?
Amy: Well, it's tricky, because answering that question honestly is one of the things I tend not to do because it upsets you.
Sheldon: Well, that's very upsetting.
Amy: Like I said.

Sheldon: What other things don't you do because of me?
Amy: Remember last week when we went to that dueling piano bar I was so excited about?
Sheldon: No.
Amy: Well, now you're getting it.

Penny: So, what is all that stuff?
Amy: This is a portable electroencephalogram. I'm doing research on emotions and brain activity. So when you start crying, I can see which region of the brain is activated. Then I'm going to stimulate the analogous area in the brain of a rhesus monkey and see if he cries. Cool, huh?

Amy: Sheldon, the only way to get past this fear is to interact with it. Just like you did with the mailman.

Penny: Look, it's fine. We're not getting married, okay? We're keeping things, you know, homeostasis.
Amy: It's so cute when she tries.