Sheldon: You know, its a tad old-school, but my father was not one to spare the rod when my brother would sneak into his truck and drink his driving whiskey.
Amy: You want to spank me?

Amy: Well, Howard's never gonna go to space again, but Sheldon will always be a genius.
Bernadette: You're right. And, I'm sure Sheldon will get a fancy parking spot again if and when he makes a worthwhile contribution to science.
Amy: If and when?

Amy: Bernadette, I want to thank you for allowing me to be your maid of honor. I also want you to know that I will be happy to do it again if this marriage craps out.

Amy: Stop it! Today is not about you, it's about Howard and Bernadette, and me!

Amy: We could go to the cadaver lab at UCLA and play real-life Operation.
Leonard: Uh-uh.
Sheldon: No.
Penny: I don't think so.
Amy: Are you sure? I mean, the nose doesn't light up, but if the corpse is fresh enough, sometimes you can get the leg to jerk.

Penny: You look beautiful.
Amy: Of course I do, I'm a princess and this is my tiara!

Amy: If Sheldon proposed to me during sex, my ovaries would grab onto him and never let go.

Amy: It's not for us to judge. We're just here to provide comfort and support while you come to grips with what a despicable thing you've done.

Penny: You know Amy, when we say we're having girl talk, it doesn't mean that we just have to talk about our ladyparts.
Amy: That's a shame. I had a real zinger about my tilted uterus.

Amy: We're playing doctor. Star Trek style.

Amy: There's not a hair on my body I wouldn't let this woman trim.

Amy: Before I met you, I was a mousey wallflower. But look at me now. I'm like some kind of downtown-hipster-party girl with a posse, a boyfriend and a new lace bra that hooks in the front, of all things!

Amy: Goodnight, painting Penny. Goodnight, real Penny.
Penny: Goodnight, real Amy.
Amy: You don't have to say goodnight to painting Amy, because she's never leaving.

Amy: I'll let you in on a little secret. Originally, we were painted nude. But I had him add clothes cause I thought it was an unnecessary challenge to our heterosexuality.
Penny: Yeah, good call.
Amy: But, if you ever change your mind, all it would take is some warm, soapy water and a couple of sponges.
Penny: You're talking about the painting, right?
Amy: Sure.

Amy: Oh, are we nervous, Dr. Cooper?
Sheldon: No. What you see is a man trembling with confidence.