Bernadette: That's pretty big talk for a man with a closet full of magic tricks at his mother's house.

Bernadette: (Yelling at Raj) I'M NICE TO EVERYONE!

Priya: What happened?
Bernadette: Howard's mother had a heart attack because I have sex with him and she can't.

Bernadette: Do you want me to spill hot soup on her?
Penny: Oh, please, you're not that kind of person.
Bernadette: I know. But if she orders something low-fat I'll totally give her the full-fat version.

Bernadette: All right. Here you go. Two lemonades, one iced tea and a root beer for Priya.
Priya: Is it diet?
Bernadette: That's what you ordered.

Bernadette: She thinks she got food poisoning from that deli and she just wanted to make sure I was okay.
Howard: And are you?
Bernadette: No, because I'm engaged to a putz! You let me believe I was the reason she had a heart attack.
Howard: Well, based on the available evid-
Bernadette: Shut up! She said I'm a wonderful girl and that you're lucky to have me.
Howard: Where are you going?
Bernadette: (sounding like Mrs. Wolowitz) To the toilet! Is that okay with you?

Bernadette: That bitch!

Amy: She always this crabby when she urinates?
Bernadette: We're really not that close.

Bernadette: I can't do this any more! I'm a good girl. I went to Catholic school!

Amy: I must say, Penny, this is great fun.
Penny: Glad you're enjoying yourself.
Amy: Until I met you and Bernadette, my trips to the bathroom had been entirely focused on elimination. Now they have a delightful social aspect.
Bernadette: Amy, you must've been in the bathroom with other women before.
Amy: Of course I have. But they were strangers and seemed off-put when I engaged in friendly stall-to-stall chit chat.
Bernadette: Some women don't like to get chummy when their panties are down.

Howard: Okay, I'm still trying to work this out. How did Penny meet an astronaut?
Bernadette: I don't know. The regular way people meet astronauts.
Howard: Most of those guys live in Texas.
Bernadette: Obviously, this one doesn't.
Howard: Okay.
Bernadette: Leonard lives here. Priya's from India. People meet, Howard. God!
Howard: Fine.
Bernadette: You've met lots of astronauts, and I've never grilled you about that. I'd thank you to extend me the same courtesy.

Leonard: I still can't get over the fact that she got a big movie part. Not that I care what my ex-girlfriend's up to, 'cause I don't.
Bernadette: Maybe that's where she met the astronaut, all right?
Priya: I'm sorry. What would an astronaut be doing working on a movie?
Bernadette: He's a consultant.
Leonard: I thought the movie was about 18th-century Vienna?
Bernadette: He can't have a hobby? Excuse me, I have to pee. Or is that implausible, as well?

Bernadette: Oh, I totally want to see Sheldon dance. I bet he looks like a spider on a hot plate.

Penny: Did you know last weekend Priya took Leonard rollerblading at the beach? Can you believe that?
Bernadette: I feel like I'm supposed to say that bitch, but I don't have enough information.
Penny: I am the one who spent two years trying to get him to even go to the beach in the first place. And he was so phobic about stepping on medical waste, I had to carry him to the water.
Bernadette: I took Howard to the beach once. He almost burst into flames like a vampire.

Penny: So what's the thanks I get for turning Leonard into quality boyfriend material? I have to tiptoe around his new girlfriend.
Amy: I think you're on.
Bernadette: Oh. That bitch!