Howard: That's not true. My happiness is not dependent on my best friend being miserable and alone.
Raj: Thank you.
Howard: Although, I'd be lying if I said it wasn't a little bit of a perk.

Raj: You know what? Even though I don't have a girlfriend, I can still have a good time on Valentine's Day.
Howard: Trust me, you can't. I've tried.
Raj: No, no, no, I’m going to have a me day. First I’m going to go to one of those spas in Koreatown, take a steam and get a massage. Then I’m going to stop at a pet store and get licked by puppies.

Sheldon (to himself): Structure, constant structure, one atom.
Howard: Boy, he's really gone, isn't he?
Leonard: Yeah, this morning he used a stick of butter as deodorant.
Howard: I thought I smelled popcorn.

Leonard: You know what? Let's just get a pizza.
Sheldon: Good idea. We'll go to Corleone's.
Howard: Sure, no mobsters there.

Howard: Now, inside, we've got motion detectors, infrared sensors, and cameras connected to a server running state-of-the-art facial recognition software.
Leonard: Where did you get all this stuff?
Howard: I got a buddy over at the Department of Defense.
Leonard: He just gave it to you?
Howard: I'm sure he would have if I had asked. Ironically, their security isn't all that good.

Howard: Oh, come on. So you were the victim of a crime. That's part of life. When my great-grandfather first came to this country, he put all his hopes and dreams into this little butcher shop he ran on the Lower East Side of New York. You know what happened? Every customer who walked into that butcher shop and asked for a pound of liver, got ripped off. But, those people moved on, and so should you.

Leonard: How can I go out with a woman who believes in psychics?
Howard: Hey, I once dated a girl who believed she was abducted by aliens.
Leonard: And that didn't bother you?
Howard: Au contraire. It meant that she was gullible and open to a little probing.

Howard: I don't like to kiss and tell, but somebody made it to eighth base.
Leonard: What the hell is eighth base?
Howard: Seventh base with shirt off. Well, my shirt.

Howard: Let me show you another way to look at this. Here we have the universe of all women. These are the ones you want to sleep with. These are the women who believe exactly what you believe. These are the women who would be willing to sleep with you. And right there in the little triple intersection is your ideal mate. Odds are she's a short physicist with low self-esteem who lives in a government research facility in China.

Leonard: Look at us. Getting ready for a double date with actual women who publicly acknowledge they're our girlfriends.
Howard: Yes, actual women are the best.
Sheldon: I don't understand. What other kind of women are there?
Leonard: Howard, artificial women are your department. You want to take this?
Howard: No, it would just freak him out.

Bernadette: So, what should we talk about?
Howard: Well, we could always learn more about why people who believe in psychics are idiots. Leonard?

Leonard: Come on, Howard, Bernadette, you're both scientists. Help me out here.
Howard: What do you think? Want to jump right into the middle of another couple's argument?
Bernadette: No, thank you.
Howard: Sorry.

Howard: Are we taking our relationship frustrations out on innocent Cylons?
Leonard: It's not just Cylons. Superman's next.
Howard: All right, I was going to try to squeeze in a little more mocking before lunch, but I can come back later when you don't have a high-powered weapon.

Leonard: Howard, relax. I am not interested in your girlfriend.
Howard: I hope not. Because you don't wanna mess with me. *Gets in Leonard's face* I'm crazy.

Howard: Bernadette say fo'shizzle to my nerdizzles.