Penny: What's the word, hummingbird?

Penny: What's the gist, physicist?

Sheldon: What about Nebraska?
Penny: Oh hell with Nebraska. I'm gonna be a star!

Penny: Oh, my God, I screwed up everything. I hurt Leonard, I hurt Raj, I mean, what is wrong with me? I feel like two totally different people, Dr. Jekyll and Mrs. Whore.

Penny: You know, I've done this before. In kindergarten, I was supposed to marry Jason Sorensen at recess, but by the time my class got out there, he was already engaged to Chelsea Himmelfarb. So what did I do? Hung upside down from the monkey bars, let all the boys see my underpants.

Penny: You know what? Let's get out of here.
Amy: Where are we going?
Penny: Somewhere where no one's seen me naked. We may have to drive awhile.

Penny: You know, I don't even know what the point of me staying in L.A. is. I haven't gotten a single acting job since I moved out here. The closest I came was last month, I got a callback for a hemorrhoid commercial.
Amy: Oh, I could so see you being the face of hemorrhoids.
Penny: I know, right?

Raj: Well, uh, as your friend, you might like to know that, um, we didn't have sex in the conventional sense.
Penny: Oh, God. Did you pull some weird Indian crap on me?

Penny: Well, I already talked to Raj, but I wanted to apologize to the rest of you for, you know, everything.
Raj: Please, Penny, let me. We've decided to let our crazy, wonderful night together be just one of those memories you have and can call to mind when you're feeling blue or you're in the shower. (places a hand on Penny's shoulder)
Penny: Hey, what you doing, Quick Draw?
Raj: Sorry. Go on.

Penny: Really still can't talk to me?

Penny: So that means, you're a doctor, you're a doctor, you're a doctor, you're a doctor and, Howard, you know a lot of doctors.

Sheldon: Here's an interesting fact about alcohol: Man is not the only species that ferments fruit in order to become intoxicated. Can you guess what the other is? Hint: sometimes they pack the alcohol in their trunks.
Penny: Monkeys.
Sheldon: When does a monkey have a trunk?
Penny: When a suitcase just won't do.

Penny: Can I tell you a secret?
Raj: Yeah.
Penny: I screwed up. Leonard's a great guy. Never should have broken up with him.

Penny: Oh, my God, you’re about to jibber jabber about jibber jabber.

Penny: Hey, do me a favor and take table seven.
Bernadette: You mean the one with my one hundred and eighteen-pound rock-hard stud of a fianc who's prone to canker sores and pinkeye?
Penny: Nah, I prefer to look at it as the one with my ex-boyfriend and his gorgeous, successful and sophisticated girlfriend, who makes me feel like a toothless Okie.