Sheldon: Pee for Houston, pee for Austin.
Pee for the state my heart got lost in.
And shake twice for Texas.

Howard: I have a two-part question.
Sheldon: Go ahead.
Howard: A: Are you kidding? And B: Seriously, are you freaking kidding me?
Sheldon: A: I rarely kid, and B: when I do kid, you will know it by my use of the word "Bazinga".
Howard: So you're saying the two of you are going to be sleeping in the same bed?
Sheldon: Yes. Bazinga.

Raj: I don't wanna sit by myself.
Sheldon: That's what Typhoid Mary said and clearly, her friends buckled.

Sheldon: Oh, Leonard, I have something for you. Per our roommate agreement, this is your 24-hour notice that I will be having a non-related female spending two nights in our apartment.
Leonard: When you say non-related female, you still mean human, right?
Sheldon: Of course. Pets are banned under the roommate agreement, with the exception of service animals, such as seeing eye dogs and, one day, cybernetically enhanced helper monkeys.

Leonard: Why is a world-renowned scientist staying in our apartment instead of a hotel?
Sheldon: Well, she doesn't care for hotels. And who can blame here? Windows that don't open, multi-user linens, keys shaped like credit cards, as if one walks around with unassigned slots in one's wallet.

Sheldon: A word of warning. My guest is a noted physicist and the leading expert on quantum cosmology, so please try to avoid wasting her time with female jibber jabber.
Penny: Female jibber jabber?
Sheldon: Shoe sales, hair styles, mud masks, gossip about your friends Brad and Angelina.
Penny: Oh, they're not my friends.
Sheldon: I'm not surprised, considering the way you talk about them behind their backs.

Sheldon: In here you'll find emergency provisions. An eight-day supply of food and water, a crossbow, season two of Star Trek: The Original Series on a high-density flash drive.
Elizabeth: What if there's a disaster that destroys all the USB ports?
Sheldon: Then there's really no reason to live, is there?

*Raj sneezes*
Sheldon: Hold.
Raj: What?
Sheldon: Explain your sneeze.
Raj: I'm sorry?
Sheldon: Do you have allergies?
Raj: No.
Sheldon: Is there too much pepper on your salad?
Raj: I don't put pepper on salads.
Sheldon: I've heard enough. Sit over there.

Raj: The cosmological physicist from Princeton?
Sheldon: Yes. And until you acquire a surgical mask, please address your comments to me through a napkin.

Leonard: Why didn't you tell me you knew Elizabeth Plimpton? I am a huge fan of hers!
Sheldon: I didn't realize I was obligated to share my connection with things you're a fan of, but very well. You enjoy Canadian bacon. I've been to Toronto.

Raj: When can I sit with you again?
Sheldon: When I've seen two consecutive negative throat cultures spaced 12 hours apart. You know the drill. All right, if you'll excuse me, I am off to start a prophylactic course of antibiotics.

Sheldon: Oh, Penny, excellent. I have a question about these maxi pads. Are the wings truly functional or have I fallen victim to marketing hype?
Penny: What? What are you doing with, what?
Sheldon: The stock boy at Walgreens was frustratingly uninformed on the subject.

Sheldon: Now listen, one of the great minds of the 21st century is about to play host to one of the other great minds of the 21st century. So pay attention. Years from now, my biographer might ask you about this event.
Leonard: Oh, I have so many things to tell your biographer.

Dr. Elizabeth Pimpton: Ah, Dr. Cooper, thank goodness. I completely forgot your address. But then I remembered that Id written it on my hand. Lucky for me, I didn't confuse it with what I'd written on my other hand, which are the coordinates for a newly discovered neutron star. 'cause if I tried to go there, I'd be crushed by hypergravity. Anyway, hello.
Sheldon: Hello.
Dr. Elizabeth Pimpton: Nice to finally meet you in person.
Sheldon: I would imagine it is.

Leonard: (To Dr. Elizabeth Plimpton) I think any university would want you. Except, of course, any university that had already had you. Because they would've already wanted you before they, you know, got you.
Sheldon: From the mind that brought you hi-lo.