Sheldon: I thought where you come from they don't have emotions.
Spock Doll: I come from a factory in Taiwan.

Sheldon: I always thought if I were enslaved, it would be by an advanced species from another planet. Not some hotsie-totsie from Glendale.

Leonard: In what universe is that a present?
Sheldon: It's not a present, it's the present. Look. There's you and me. It's Penny and Amy. We're playing Pictionary. In the present.
Penny: Oh, my God, we're gonna kill them.

Amy: Well, you got me something. Here.
Sheldon: Cookies?
Amy: They're your MeeMaw's Christmas cookies. I called and got the recipe.
Sheldon: They're perfect. It tastes like her hugs.
Amy: Merry Christmas, Sheldon.
Sheldon: I can't believe this. You're happy. I'm happy. Maybe a holiday that's all about giving isn't so - Get your hand out of that box!

Amy: That's fascinating. I can't wait to read it.
Sheldon: Oh, me as well. Please email it to [email protected] Why .biz? Because I just gave you the business. And also bazinga.com was taken.

Penny: Hey, I don't think she's wrong about you going too slow in the relationship.
Sheldon: Too slow?
Penny: Yeah, you've been going out for years. You haven't even slept together.
Sheldon: That's right. It's called foreplay.

Sheldon: (3 knocks) Birthday girl! (3 knocks) Birthday girl! (3 knocks) Birthday girl!

Penny: I'm a Sagittarius, which probably tells you way more than you need to know.
Sheldon: Yes, it tells us that you participate in the mass cultural delusion that the sun's apparent position relative to arbitrarily defined constellations at the time of your birth somehow affects your personality.
Penny: Participate in the what?

Leonard: You are not Isaac Newton.
Sheldon: No, no, that's true. Gravity would have been apparent to me without the apple.

Sheldon: When I try to deceive I have more nervous ticks than a lime disease research facility. It's a joke. It relies on a homonymic relationship between the tick the blood sucking arachnid, and tick the involuntary muscular contraction. I made it up myself.

Sheldon: I am a grown man. I am a professional scientist. And I currently occupy the moral high ground.
Mary: Go to your room.
Sheldon: But I occupy the moral high ground.
Mary: Go to your room.
Sheldon: But I'm a professional scientist.
Mary: Go to your room!
Sheldon: *Backs away to his room* I'm a grown man.

Amy: Kiss me where I've never been kissed before?
Sheldon: You mean like Salt Lake City?

Sheldon: Score 1 for liquor and poor judgement.

Leonard: Sheldon lives in fear of the three-tined forks.
Sheldon: Three tines is not a fork. Three tines is a trident. Forks are for eating, tridents are for ruling the seven seas.

Sheldon: I decided to take your advice and have arranged to go on a date with Amy Farrah Fowler.
Penny: Oh, that's great. Have fun.
Sheldon: Wait, you have to drive me.
Penny: What?
Sheldon: You know I don't drive.
Penny: Well, go ask Leonard.
Sheldon: I did; he said, and I quote: "Ask Penny, it was her cockamamie idea."
Penny: Leonard said "cockamamie"?
Sheldon: Actually, I'm paraphrasing. Having been raised in a Christian household, I'm uncomfortable with the language he used. And to be honest, I'm not entirely comfortable with "cockamamie".