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Quote from Howard in the episode The Cooper-Nowitzki Theorem

Penny: Whats Sheldon's deal? Is it girls, guys, sock puppets?
Howard: We operate on the assumption that Sheldon has no deal. Though we have many theories about how he might reproduce. I'm an advocate of mitosis.
Penny: What?
Howard: I believe that one day Sheldon will eat an enormous amount of Thai food and spilt into two Sheldons.

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