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Quote from Bernadette in the episode The Proton Transmogrification

Bernadette: I got into science because I was always the smallest kid in the school. I thought if I became a scientist I could invent a formula that made me taller.
Amy: That's cute.
Bernadette: I thought it was working for a while, but then I found out my brother was just lowering the pencil marks on the door frame.

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