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in the episode The Decoupling Fluctuation
Leonard: Okay, I think I understand.
Sheldon: You do?
Leonard: The guy who seems like an emotionless robot is you, but your relationship with Amy is causing you to transform into a red-blooded man with sexual desires.
Sheldon: That is literally the stupidest thing I've ever heard.
This helps us figure out whether you are a human or a cyborg.