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in the episode The Irish Pub Formulation
Sheldon: And here is the clincher, a lock of Maggie's flaming auburn hair.
Leonard: Where did you get that?
Sheldon: From an orangutan in the primate lab.
Leonard: An orangutan?
Sheldon: Well, no one's going to run a DNA test on it, Leonard. Honestly, you over think everything.
This helps us figure out whether you are a human or a cyborg.