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Quote from Sheldon in the episode The 2003 Approximation

Sheldon: I appreciate your interest in the apartment. I just need to ask you a few standard questions.
Applicant: Sure.
Sheldon: It says here you're a chemist. Which element on the periodic table do you feel is too big for its britches?
Applicant: Is that supposed to be a joke?
Sheldon: Looks like argon's not the only one with an attitude problem.

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