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Quote from Leonard in the episode The Meemaw Materialization
Sheldon: Uh, Meemaw, this is Leonard. Leonard, this is my Meemaw.
Leonard: Hi. So nice to finally meet you. Let me take this for you, Meemaw.
Meemaw: Thank you.
Sheldon: No. Now you call her Constance. I call her Meemaw. You have your own Meemaw.
It's not my fault she died when you were four.
Meemaw: Is that nice to say to your friend?
Sheldon: It isn't, Meemaw. Sorry, Leonard.
Leonard: Can you please live with us forever?
This helps us figure out whether you are a human or a cyborg.