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in the episode The Line Substitution Solution
Sheldon: All right, back to learning.
Sheldon: Oh, easy. Bill Nye the Science Guy.
Penny: Or as I know him?
Sheldon: Creepy old dude from Dancing with the Stars.
Penny: Ding, ding, ding, ding, ding.
This helps us figure out whether you are a human or a cyborg.