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in the episode The Hawking Excitation
Penny: Why are you washing Howard's man panties?
Sheldon: Because if I don't, he won't give my paper to Stephen Hawking. He's a famous physicist.
Penny: Yeah, yeah, I know. He's the wheelchair dude who invented time.
Sheldon: That's close enough.
This helps us figure out whether you are a human or a cyborg.