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in the episode The Brain Bowl Incubation
Sheldon: How much will it hurt?
Amy: It's just a tiny skin sample. You saw me do it to myself.
Sheldon: On a scale of one to ten, where one is a pebble in your shoe and ten is the monkey you thought was your pet biting your face off.
Amy: A two.
Sheldon: Eating a whole Altoid?
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