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in the episode The Precious Fragmentation
Howard: So, Sheldon, how's it feel to get beaten up by a girl?
Sheldon: It's not the first time. I have a twin sister whose assaults began in utero. If only I'd had the presence of mind to reabsorb her, then I'd have a mole with hair in it instead of a tedious yearly Christmas letter.
This helps us figure out whether you are a human or a cyborg.