Penny: Anyway, I was talking to Leonard this morning and I think he feels really bad about it.
Penny: Well, how do you feel?
Sheldon: I don't understand the question.
Penny: Well I'm just asking if it's difficult to be fighting with your best friend.
Sheldon: Oh. I hadn't thought about it like that. I wonder if I've been experiencing physiological manifestations of some sort of unconscious emotional turmoil.
Penny: Wait, what?
Sheldon: I couldn't poop this morning.