Sheldon: Hello? What did we just learn about the end of business meetings? [everyone groans as they shake each other's hands]

Amy: Sheldon.
Sheldon: What? Did you finish? Great job.

Leonard: You pick up your dresses?
Amy: Yep. The tailor had to take mine in and let Penny's out. Best day of my life.
Sheldon: What about the day you met me?
Amy: I stand by my statement.

Amy: I think you need to do some editing, like maybe cut out all that stuff about your childhood.
Sheldon: Are you kidding? Growing up in the backwoods of East Texas is what makes me warm and relatable.
Amy: Well, what about all these pages calling out everyone who said you wouldn't succeed?
Sheldon: I told them all they would rue the day. How is it gonna make me look if the day finally comes, and they're not filled with rue?

Leonard: You are a selfish jerk. To hell with you and your Nobel Prize.

Amy: Do you want to go back to the apartment and see me try on my dress?
Sheldon: Shouldn't I see it for the first time at the Nobel ceremony?
Amy: It's not a wedding.
Sheldon: Okay. Well, give me a minute to think of another reason I don't want to see it.

Leonard: Oh, don't slam the-
Sheldon: Don't slam the [gasps] That was exhilarating.

Amy: Sheldon, this isn't about ruing. This is about humbly accepting a great honor.
Sheldon: Amy, we won the Nobel Prize in Physics. Humility is for people who win the goofy Nobels like Literature, Economics and Peace.
Amy: Please tell me that's not in your speech.
Sheldon: Oh. I can cut it, but it's the only joke I have.

Sheldon: Well, I hate to say it, but I think everyone is being incredibly selfish.
Amy: Well, you would be the authority on the subject.
Sheldon: What does that mean?
Amy: Sheldon, no one is happier than I am to win the Nobel. But it's not more important than our friends.
Sheldon: How can you call them friends when they're abandoning us?
Amy: They're abandoning us because you broke their hearts.
Sheldon: I didn't mean to.
Amy: I know! You never mean to. That's the only reason people tolerate you!
Sheldon: Does that include you?
Amy: Sometimes, yeah.

Sheldon: What would you like me to say?
Leonard: How about congratulating us?
Sheldon: Are congratulations even in order? I didn't think Penny wanted children.
Leonard: Well, she didn't, now she does. And just so you know, we weren't gonna tell anybody so we wouldn't upstage your big day.
Sheldon: Oh, please, you couldn't upstage us. We won a Nobel Prize. Any idiot can have a baby.
Howard: Hey. What's going on?
Sheldon: Case in point.

Bernadette: You realize it's been years since we've got away just the two of us.
Howard: I know. I can't wait. Fancy hotel room. The big bed.
Bernadette: Yeah. We're gonna sleep our asses off.

Amy: Thank you, your majesties. Thank you to the Nobel Committee. We are deeply honored. I would just like to take this moment to say to all the young girls out there who dream about science as a profession: go for it. It is the greatest job in the world. And if anybody tells you you can't, don't listen. And now, speaking of not listening, my husband, Dr. Sheldon Cooper.

Sarah Michelle Gellar: Just to be clear, this isn't a date.
Raj: Yeah, I know.
Sarah Michelle Gellar: Then why are you holding my hand?

Leonard: What?
Amy: Sheldon has something he'd like to say.
Sheldon: I'm sorry I didn't react appropriately. You and Penny are bringing new life into the world. Congratulations. I can't wait to meet it.
Leonard: "It"?
Sheldon: That's a gender-neutral pronoun. If you're offended, take it up with the English language.

Sheldon: All right, bagels down. Before we head to the airport, I'd like to go over a few things.
[others groan]
Sheldon: From the moment we step off the plane, each and every one of you is an ambassador for Amy and myself.
Howard: [to Bernadette] I told you these tickets weren't free.