Sheldon: Excuse me, are you saying that Wil Wheaton, a.k.a. Ensign Wesley Crusher on Star Trek: The Next Generation, is going to be participating in your tournament?
Stuart: I'm sorry, did I rob you of the opportunity to stumble onto that for yourself?
Sheldon: No, wait, you don't understand. Growing up, I idolized Wil Wheaton. You know, Wesley Crusher had an eidetic memory just like me.
Raj: Oh, what a coincidence. Maybe you can discuss that with him while you're playing in the tournament. Sign here.
Sheldon: Yeah, I was such a fan that in 1995, I traveled 10 hours by bus to a sci-fi convention in Jackson, Mississippi wearing my Starfleet Academy cadet uniform in order to meet Wil Wheaton and get him to autograph my mint-in-package Wesley Crusher action figure.
Raj: Oh, It'll be like a reunion then. Sign here.
Sheldon: (Mood changes) Yeah, my arduous journey, however, was for naught. Although advertised to appear, he did not show up. It was at that moment I vowed eternal hatred for Wil Wheaton.
Raj: Okay, great, you can tell him you hate him, sign here.
Sheldon: It might interest you to know that Wil Wheaton currently ranks 6th on my all-time enemies list, right between director Joel Schumacher, who nearly destroyed the Batman movie franchise, and Billy Sparks, who lived down the street from me and put dog poop on the handles of my bicycle.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Bernadette: Does your mother call you every day at work to see if you had a healthy lunch?
Howard: My mother calls me every day at work to see if I had a healthy bowel movement.

Wil Wheaton: Game over, Moonpie.

Wil Wheaton: Did that guy just say "Revenge is a dish best served cold" to me in Klingon?