Leonard: You know we could throw a dinner party too. Maybe even ask everyone to get dressed up.
Penny: Sure. Just when you say dressed up, you mean nice clothes, right? Not like capes and tights and crap
Leonard: Yes. Although...
Penny: No.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Howard: I'm not signing a prenup.
Penny: All right, Howard Wolowitz, listen up! You sign anything she puts in front of you, because you are the luckiest man alive. If you let her go, there is no way you can find anyone else. Speaking on behalf of all women, it is not going to happen, we had a meeting.

Sheldon: Did you also have a dog? Because I found what appears to be a battery-operated chew toy.
Penny: Party's over. Party's over.

Bernadette: I told you you shouldn't have espresso after dinner. I know the little cups make you feel big but it's not worth it.

Bernadette: You can't just throw everything in the closet.
Howard: Hey, you can tell me what to do and how to do it, but not both at the same time. This isn't sex.