Bernadette: Oh my God! You did not just slow down for a bird! You know they fly, right?

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Bernadette: You better find my husband's mother, 'cause one way or another we're walking out of this airport with a dead woman.

Amy: As my mom used to say, "When you're doing a puzzle, it's like you've got a thousand friends." She was full of fun lies like that.

Penny: Run to India.

Sheldon: My brain is better than everybody's!