Howard: My mom's been to Arizona. She rode one of those mules down in the Grand Canyon. Long story short: they had to shoot it.
*Blank look from Bernadette's father*
Howard: ... because she's so fat.
*door rings*
Howard: I'll get the door while you finish laughing.

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Howard: So you can never take it (the sweater) off?
Leonard: No.
Raj: Not even to sleep?
Leonard: No.
Howard: So you're just an idiot?
Leonard: It's called proving a point.
Howard: Is the point you're an idiot?

Bernadette: Maybe we should get one of those machines to help her up the stairs.
Howard: You mean a fork lift?

Penny: Howard, cow tipping - real or not?
Howard: I'm going to say not. That's just based on me trying to roll my mom over when she's snoring.

Amy: It says here you can get an annulment if any of the following conditions were met: Were you unable to consummate the marriage?
Sheldon: Penny!? Ha! Next ...

Mike: I don't know what's scarier: the bathroom clowns or the woman that put them there?
Sheldon: All I know is you can only fit one of her in a car.
*Howard walks in*
Sheldon: And there's the clown that came out of her!