Amy: It's fine. I'm used to being the girl who never gets looked at twice. I didn't have my first kiss until I was 22. And the guy only did it so I'd give him back his insulin.
Bernadette: Sometimes the pancreas wants what the pancreas wants.

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Raj: Oh man, first monster I see I'm gonna sneak up behind him, whip out my wand and shoot my magic all over his ass!
Stuart: Do you hear yourself when you say these things?

Raj: Doesn't anyone have a rod of resurrection? Because if you've got one, I need it bad. Get in here with your rod and give it to me.
Stuart: Okay, you need to say these things in your head before you say them out loud.

Sheldon: Fun? Mixing Dungeons and Dragons with Christmas is like making a sandwich of grape jelly, the best-tasting jelly, and petroleum jelly, the worst-tasting jelly.