Bernadette: Sheldon, I've been cooking all day.
Sheldon: Well, now don't you feel silly.
Bernadette: (To Howard) Show him the closet.

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Leonard: You don't go into science for the money.
Bernadette: Speak for yourself. Last month my company both invented and cured restless eye syndrome. Ka-ching, ya blinky chumps!

Bernadette: I told you you shouldn't have espresso after dinner. I know the little cups make you feel big but it's not worth it.

Sheldon: What can I do for you ladies?
Amy: You have something we want.
Sheldon: Oh, dear. My mother warned me this is what happens to pretty boys in the big city.
Penny: No, we just want information.
Sheldon: Oh. I've got that spades. Ravage me.

Sheldon: Did you also have a dog? Because I found what appears to be a battery-operated chew toy.
Penny: Party's over. Party's over.