Leonard: Here you go, Copenhagen boy, how about a taste of Hans Christian Hand Grenade.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.

Howard: Try telling him it's a non-optional social convention.
Penny: What?
Howard: Just do it!
Penny: It's a non-optional social convention.
Sheldon: Oh, fair enough.
Howard: He came with a manual.

Sheldon: What computer do you have? And please don't say a white one.

Store Clerk: Excuse me, Sir, you don't work here.
Sheldon: Yes, well apparently neither does anyone else.