Penny: And you know what the best part is? We took our time. I mean, we met, we were friends for a couple years, then we got together, and then we got untogether, then we worked out all our problems, and now we know everything about each other, we can just go forward with no surprises and no regrets.
Leonard: Right. No surprises.
Penny: And no regrets.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Howard: I'm not signing a prenup.
Penny: All right, Howard Wolowitz, listen up! You sign anything she puts in front of you, because you are the luckiest man alive. If you let her go, there is no way you can find anyone else. Speaking on behalf of all women, it is not going to happen, we had a meeting.

Leonard: What am I supposed to do?
Penny: Err, keep your mouth off other women.

Penny: Wait, what is wrong with you two? He was talking about television during their date night.
Sheldon: Oh, not just date night. Our 5th anniversary.
Penny: Okay, see, that's even dumber than you wondering if being bitten by a goat would give you the powers of a goat.
Sheldon: If that happens, don't make me wait ten years to watch you eat a tin can.

Sheldon: Amy's mad at me, and I'm not clear why.
Penny: Okay, were you talking before she got upset?
Sheldon: Yes.
Penny: That's probably it.