Penny: Gosh, I worked my ass off today. This is exactly what I needed.
Leonard: Great. Just relax and enjoy. Tonight is all about you.
Penny: Aw, thank you.
Leonard: So, where exactly are we in this relationship?
Penny: Oh, come on.

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Raj: [to Amy] If you were having Sheldon's baby, would you really want him in the room?
Penny: Yeah, if he's in the room when they're making the baby, I'll give you $10.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Mrs. Wolowitz I'm not going near that fakakta thing. I'll catch a computer virus.
Howard: You can't catch a computer virus.
Mrs. Wolowitz Oh, so now you're an astronaut and a doctor?

Amy: If Sheldon proposed to me during sex, my ovaries would grab onto him and never let go.

Sheldon: Amy, when I look in your eyes and you're looking back in mine, everything feels not quite normal. Because I feel stronger and weaker at the same time. I feel excited and, at the same time, terrified. The truth is, I don't know what I feel, except I know what kind of man I want to be.
Amy: Sheldon, that was beautiful.
Sheldon: I should hope so, that's from the first Spider-Man movie.
Amy: I'll take it.