Amy: When Leonard gets back, Id love to check his serotonin levels. Do you think he'd let me draw a syringe full of his blood?
Penny: Hmm, he's not crazy about needles, but if you get him to go jogging, it'll just pour out of his nose.

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Raj: [to Amy] If you were having Sheldon's baby, would you really want him in the room?
Penny: Yeah, if he's in the room when they're making the baby, I'll give you $10.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Leonard: Do you think we can outrun him?
Sheldon: I don't need to outrun him, I just need to outrun you.

Penny: Did Sheldon change the Wi-Fi password again?
Leonard: Yeah, it's "Penny already eats our food she can pay for Wi-Fi". No spaces.

Sheldon: I'm not going to say I told you so, but we could have killed him.