Leonard: I'm sorry. I- I crossed a line. I didn't mean to!
Penny: Who says something like that right in the middle of sex?
Leonard: I don't know, it just came out. People say weird things during sex all the time.
Penny: Okay, well, they sure as hell don't say that.
Leonard: It was the heat of the moment.
Penny: No, the heat of the moment is, ooh, yeah, just like that, not will you marry me?
Leonard: I'm sorry. Just, just give me another chance.
Penny: Why, so you can crawl under the covers and go, hey, baby, want to go look for houses in neighborhoods with good schools?

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Mr. Rostenkowski: Walnut?
Howard: No, thank you. I'm allergic.
Mr. Rostenkowski: Oh, sure. My partner used to have that. He's dead now.
Howard: From nuts?
Mr. Rostenkowski: Nah, his wife shot him. But she was nuts, so in a way.

Mr. Rostenkowski: It's gonna be okay, son.
Howard: You really think so?
Mr. Rostenkowski: Of course. A pretty girl like Bernadette, she'll find a new guy.

Amy: We're playing doctor. Star Trek style.