Howard: Have you ever played a game with Bernadette?
Amy: No.
Howard: Have you ever gone into a steel cage with a wolverine?

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Josh: So, I have to ask, was the robot sexy?
Howard: It was actually just a mechanical hand.
Josh: 'Cause that's all you need, right?
Howard: You are my brother.

Sheldon: Sheldon Cooper does not cry.
Howard: That's true, you'd rust.

Penny: [to Raj] Run to India.

Amy: As my mom used to say, "When you're doing a puzzle, it's like you've got a thousand friends." She was full of fun lies like that.

Bernadette: (Shouting at another driver) Your kid might be a honor student but you're a moron!