Raj: They're my friends, and I should be happy for them. And I'm trying, but all I feel is this gnawing, empty sensation in my gut.
Stuart: I had that once. Turned out it was a tapeworm.
Raj: Cool.

Stuart: Oh, Sheldon, I'm afraid you couldn't be more wrong.
Sheldon: More wrong? Wrong is an absolute state and not subject to gradation.
Stuart: Of course it is. It's a little wrong to say a tomato is a vegetable, it's very wrong to say it's a suspension bridge.

Howard: Hang on, I know a place where you could you stay and earn some money at the same time.
Stuart: Great!
Howard: I just have to warn you: it will involve humiliation, degradation and verbal abuse.
Stuart: So, what's the catch?

Bernadette: Hey, Stuart.
Stuart: *startled* Hey.
Bernadette: Sorry, did I startle you?
Stuart: Yes, but at this point pretty much any customer does.

Sheldon: I've thought about it, and I really want to spend the rest of my life with Amy. Do I have your blessing?
Stephen Hawking: Well, Sheldon, I think you should make her finger like Saturn and put a ring on it.

Sheldon: Wait, oh, and I just I want to let you know right now that we are not getting married in a church.
Mary Cooper: That's all right, Sheldon. Anywhere Jesus is is a church.
Sheldon: Well, he won't be at our wedding.
Mary Cooper: He's in my heart, so if I'm there, he'll be there.
Sheldon: Okay, well, then, he's your plus-one. You don't get to bring anyone else.

Mary Cooper: Lord, thank You. Even though You can do anything, that was mighty impressive.