Leonard: Look, I was just speaking the truth. We're scientists. Isn't that what we're supposed to do?
Sheldon: Oh, what would you know about the truth? You thought Phantom Menace was "not half bad."
Leonard: I told you that in confidence!

Sheldon: I remember the song! It's called "Darlin'" by the Beach Boys! Oh, thank goodness! I'm not crazy! I don't have to take a pigeon as my bride!
Leonard: There goes our shot at him living on the roof.

Howard: Don't feel bad. Some day someone will be throwing out your work, too.
Leonard: That someone was Sheldon and the day was yesterday.

Professor Proton: Can I ask you a question?
Leonard: Yeah, sure.
Professor Proton: Why do you put up with Sheldon?
Leonard: Oh, you know because we're friends.
Professor Proton: Why?
Leonard: Wow, you ask really hard questions. Look, I know he can be aggravating, but what you have to remember is he's not doing it on purpose, it's just how he is. But he's also loyal and trustworthy and we have fun together.
Professor Proton: You know you're describing a dog?
Leonard: He did bite me once. But in his defense, I came up behind him while he was eating.
Professor Proton: They hate that.
Leonard: Sheldon is the smartest person I have met. He's a little broken and he needs me. And I guess I need him too.
Professor Proton: Why is that?
Leonard: Boy, you will not let this go, will you?

Leonard: Oh, hi, you wanted to see me?
Ms. Davis: Yes. I wanted to talk to you about the e-mail you sent me last night.
Leonard: I sent you an e-mail?
Ms. Davis: You bet you did. "Hello. Shalom and aloha from the grave of Richard Feynman."
Leonard: (groans) Oh, it's coming back to me.
Ms. Davis: "Please accept the following retraction: I know I said physics is dead, but it is the opposite of dead. If anything, it is undead, like a zombie. Speaking of which, if Richard Feynman came back as a zombie, I would totally let him bite me."
Leonard: Any chance that's the end?
Ms. Davis: "I got bit by a squirrel once. I had to get rabies shots. I cried so much, my mother said 'don't be a baby'. In conclusion, physics is great. Squirrels suck, and someday, I'm gonna put my mom in a cheap nursing home. Yours truly, XOXO, Dr. Leonard Hofstadter."
Leonard: I-I-I can explain.
Ms. Davis: "P.S Can you come pick us up? The Uber driver won't open the door because Sheldon is covered in blue vomit."

Bernadette: At the office, I have two assistants! I don't even know their names. I just call them Thing 1 and Thing 2.
Amy: I don't have assistants.
Bernadette: I guess that's one of the benefits of being in the private sector. That and all the money I make!

Howard: We're going to see Richard Feynman. Penny, Richard Feynman is an iconic phys-
Penny: I know who he is. Leonard dressed as him for Halloween last year.