Sheldon: Well, on the bright side, after working together for 15 years, you finally get to hear me say, "You were right."
Leonard: Yeah, you did.
Sheldon: How's it feel?
Leonard: Given I might be unemployed, bittersweet.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Leonard: Penny, as a scientist, my job is to figure out why things happen. But I don't think I'll ever understand how someone like me could get to be with someone like you. You know maybe I don't need to understand it, I just need to be grateful. I love you, Penny.

Leonard: Oh, hi, you wanted to see me?
Ms. Davis: Yes. I wanted to talk to you about the e-mail you sent me last night.
Leonard: I sent you an e-mail?
Ms. Davis: You bet you did. "Hello. Shalom and aloha from the grave of Richard Feynman."
Leonard: (groans) Oh, it's coming back to me.
Ms. Davis: "Please accept the following retraction: I know I said physics is dead, but it is the opposite of dead. If anything, it is undead, like a zombie. Speaking of which, if Richard Feynman came back as a zombie, I would totally let him bite me."
Leonard: Any chance that's the end?
Ms. Davis: "I got bit by a squirrel once. I had to get rabies shots. I cried so much, my mother said 'don't be a baby'. In conclusion, physics is great. Squirrels suck, and someday, I'm gonna put my mom in a cheap nursing home. Yours truly, XOXO, Dr. Leonard Hofstadter."
Leonard: I-I-I can explain.
Ms. Davis: "P.S Can you come pick us up? The Uber driver won't open the door because Sheldon is covered in blue vomit."

Bernadette: At the office, I have two assistants! I don't even know their names. I just call them Thing 1 and Thing 2.
Amy: I don't have assistants.
Bernadette: I guess that's one of the benefits of being in the private sector. That and all the money I make!

Howard: We're going to see Richard Feynman. Penny, Richard Feynman is an iconic phys-
Penny: I know who he is. Leonard dressed as him for Halloween last year.