Sheldon: I don't think there's anything in this jewelry store that Amy would appreciate more than the humidifier that we were just looking at at Sears.
Penny: Oh, my God, now I know what I sound like to you when I say stupid stuff.

Leonard: You said always. You'll always have feelings for me.
Penny: So?
Leonard: So, that sounds more like something you'd say if you didn't want a relationship with someone. This isn't working out, but I'll always have feelings for you. I'm sorry I slept with your best friend, but I'll always have feelings for you. Here's the thing, Lisa, I'm into dudes now, but I'll always have feelings for you.

Amy: All right, pivoting to the big question. Bernadette, on your wedding night you'll be consummating your marriage. What do you think your first sexual position will be as husband and wife?
Bernadette: Amy, please.
Amy: Keeping in mind that whoever's on top may set the tone for the marriage.
Penny: Okay, show's over.
Amy: Hey, they may conceive a child on their wedding night. Don't you think the kid might get a kick out of knowing how it happened?
Penny: I don't care. Ask her things like are you going to take Howard's name? Not who's going to sit on who.

Howard: There's fuel leaking and we're still going to go?
Mike: Don't lose your Froot Loops, Froot Loops.
Dimitri: This happens a lot. Nine times out of ten, no problem.
Howard: What happens on the tenth time?
Dimitri: Problem.

Amy: Perhaps you could assuage your guilt through altruism. ... Which word's tripping you up? Assuage or altruism?
Penny: Both.
Bernadette: You'll feel better by doing something nice for someone.
Penny: I actually knew that.
Amy: I never doubted you.

Raj: I plan on leveling up in the game, not my swimsuit size, thank you very much.

Bernadette: I don't think I can meet the girl who was always mean to me. Tammy Bodnick. One time, while I was in gym class, she stole all my clothes and left an elf costume in my locker.
Penny: Oh, that's awful.
Bernadette: Worst part was, it was too big.

Mrs. Wolowitz: Frankly, after all your sleepovers with the little brown boy, a girl is a big relief!

Penny: No, your Reebok has a gunshot wound and you have an ouchie on your pinky toe.

Mrs Wolowitz: Howard, your Froot Loops are getting soggy!

Sheldon: We're trying to think down here, you geode-loving feldspar jockeys!

Mr. Rostenkowski: Here you go.
Bernadette: "Here you go?" What am I, a football?
Mr. Rostenkowski: Like that guy could catch a football.

Howard: I haven't seen him laugh that hard since the day Leonard made that multiplication error.
Sheldon: Oh, Oh, Lord, that multiplication error! He thought he carried the one. But he didn't.
Leonard: It's not funny. That mistake got published.
Sheldon: Stop! I'm going to wet myself!

Leonard: All right, Sheldon, we're going to Wil's. This is your last chance.
Sheldon: No, Leonard, this is your last chance. One day, a historian is going to come to you and say, is it true you were friends with Dr. Sheldon Cooper? And you're going to have to choke back a hot sob of regret and humiliation as you mumble, I was, but I chose to go to a party thrown by the one kid from Stand By Me that no one remembers.

Sheldon: I'm glad we're finally getting to do something together. Just the two of us.
Mary Cooper: Sure. One thing you really miss when you're on vacation is laundry.