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'The Pork Chop Indeterminacy' - Season 1, Episode 15
Sheldon's attractive twin sister, Missy, is in town and the guys can't avoid hitting on her. As they all vie for Missy's affections, Leonard devises a plan to eliminate his rivals. Eventually, Sheldon decides he should determine who can date his sister. Meanwhile, Raj takes part in a drug trial to try overcome his selective mutism.
Air Date: May 5, 2008.