Penny: Listen, when you have kids, I'm still gonna be there. I'm gonna be their fun Aunt Penny who gives them candy, and teaches them swear words and tells them stories about what a weirdo their mother is.
Amy: I guess I could live with that. What is gonna be hard is letting go of the dream of us breastfeeding each other's babies.
Penny: And it's gonna be hard to forget you said that.

Amy: Okay, what is going on?
Penny: We just want you to be prepared for any surprises that could happen tomorrow.
Amy: What surprises?
Bernadette: We don't want to spoil anything, but you should know that Sheldon said he's ready to be physical.
Amy: You shut your damn mouth! You actually heard him say this?
Penny: Yes, he said he wants to do something to show you how much you mean to him.
Amy: I can't believe it. I don't know what to say.
Bernadette: Well, we're really happy for you and we know how much-
Amy: I do know what to say. Let's get me waxed!

Sheldon: Sheldon Cooper does not get lucky.
Amy: You and me both, brother.

Amy: Do you have any idea how hard it is to laugh at a knock knock joke that starts "Knock Knock Knock, Amy. Knock Knock Knock, Amy. Knock Knock Knock, Amy"?

Amy: Hey. Wait a minute, what about us? I mean, we're married now. Maybe we want to buy the house next door.
Sheldon: Well, Amy, we can't move. I'd have to change all the tags in my underwear.
Amy: You can buy new ones.
Sheldon: New house, new underwear. What am I, in the Witness Protection Program?

Sheldon: You're awfully quiet.
Leonard: Sorry.
Sheldon: No, I like it.
Leonard: Got a lot on my mind.
Sheldon: Would you like to talk about it?
Leonard: Not really.
Sheldon: Grape Nuts for breakfast, quiet car ride, things are really breaking my way today.

Amy: What the hell, Penny?!
Penny: I'm gonna need more than that.
Amy: You're not having kids? How could you do this to me?
Penny: How is it any of your business?
Amy: Because your kids were supposed to be friends with my kids. Who's gonna be friends with them now?
Penny: They will find other friends.
Amy: Oh, sure, 'cause Sheldon's DNA plus my DNA equals a kid who knows how to make friends. Grow up!