Leonard: You went to the comic book store by yourself?
Penny: Yeah, it was fun. I walked in and two different guys got asthma attacks. It felt pretty good.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Howard: I'm not signing a prenup.
Penny: All right, Howard Wolowitz, listen up! You sign anything she puts in front of you, because you are the luckiest man alive. If you let her go, there is no way you can find anyone else. Speaking on behalf of all women, it is not going to happen, we had a meeting.

Leonard: Once you open the box it loses its value.
Penny: Yeah, yeah. My mom gave me the same lecture about my virginity. I gotta tell you, it was a lot more fun taking it out and playing with it.

Sheldon: I thought where you come from they don't have emotions.
Spock Doll: I come from a factory in Taiwan.

Raj: No, I'm not gay. If anything, I'm metrosexual.
Dr. Koothrappali: What's that?
Raj: It means that I like women, as well as their skin-care products.