Penny: I just got a part on a TV show.
Amy: Congratulations!
Leonard: That's great. Guys ...
The guys: Yeah ...
Amy: What's the show?
Penny: NC - I I? or, you know, NC - S T D. I don't know. It's the one with all the letters.

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Raj: [to Amy] If you were having Sheldon's baby, would you really want him in the room?
Penny: Yeah, if he's in the room when they're making the baby, I'll give you $10.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Amy: Do you have any idea how hard it is to laugh at a knock knock joke that starts "Knock Knock Knock, Amy. Knock Knock Knock, Amy. Knock Knock Knock, Amy"?

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Sheldon: Leonard, do you think I'm funny?
Leonard: No. Do you?
Sheldon: I think I'm hysterical.
Leonard: I take it back. That was funny!