Mike Massimino: You know how astronauts need to have the right stuff?
Howard: Sure.
Mike Massimino: The stuff you have is wrong.

Bernadette: Besides, Penny and I are having a girl's night tonight.
Amy: Girls night, what does that entail?
Bernadette: Oh you know, girls get together hang out share girl talk.
Amy: I'm a girl.
Bernadette: Oh well maybe you could join us. I'll ask Penny.
Amy: No need, Penny and I are very close.
Leonard: You are?
Amy: Yes, In fact our mensies are synchronized.

Penny: You locked them in your basement?
Dr. Lorvis: Well, they're not locked in. The door just sticks.
Penny: Okay, so how do they unstick it?
Dr. Lorvis: They'd need the key.

Penny: Okay, you can't just go chasing after every girl who's nice to you.
Dr. Lorvis: Well, that's not what Sheldon says, and he seems to know his way around the ladies.

Bernadette: I think what we're all trying to say is that you don't seem to be remembering how traumatic the experience was for you.
Raj: Like how women often forget the pain of childbirth.
Mike Rostenkowski: Like a woman. Great analogy.

Sheldon: I've changed. Like the frog who's put in a pot of water that's heated so gradually, he doesn't realize he's boiling to death.
Penny: Or you're the frog who's been kissed by the princess and turned into a prince.
Leonard: Or you're just a tall, annoying frog.

Amy: I'm not surprised you want to end the relationship. I'm a little surprised you didn't get AppleCare.