Penny: Okay, just to be clear. You are asking me for help because I know something that the brilliant Dr. Sheldon Cooper doesn't.
Sheldon: I suppose that's one way to look at it.
Penny: I think it's the only way to look at it.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Penny: Sheldon, what did we say about being a nicer friend?
Leonard: Thank you.
Penny: Leonard, what did we say about being a gullible weeny?

Leonard: What am I supposed to do?
Penny: Err, keep your mouth off other women.

Raj: Dance number aside, I'm so not gay.

Penny: Mrs. Cooper? Hey, it's Penny. I think I broke your son. Hold on. Talk to your mother.
Sheldon: (Crying) Mommy, I love you. Don't let Spock take me to the future!

Raj: I know the feeling. It's like accidentally walking into a gay bar and then having no one hit on you. It happened to a friend of mine.