Penny: What you doing? Trying to contact your home planet?
Sheldon: I'm practicing my theremin.

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Raj: [to Amy] If you were having Sheldon's baby, would you really want him in the room?
Penny: Yeah, if he's in the room when they're making the baby, I'll give you $10.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Sheldon: I'm not saying that all senior citizens that can't master technology should be publicly flogged. But, if we made an example of one or two it might give the others incentive to try harder.

Raj: Ooh, Leonard is going all alpha nerd on Sheldon's ass.

Leonard: I had a great idea. Do you know how we're always having to stop and solve differential equations, like when you're doing Fourier equations or using the Schroedinger equation?
Sheldon: Howard doesn't, he's only an engineer.