Sheldon: No. I quit. [After Sheldon stands up, there is a crashing sound from the driving simulation. Then pained noises from animals]
Leonard: Aw, the pet store?
Sheldon: Remind me to compliment Wolowitz on the software, it's amazingly detailed.

Leonard: So wait,you're just gonna give up?
Sheldon: No, I'm not giving up. I never give up.
Leonard: So what is it you're doing?
Sheldon: I'm transcending the situation. I'm clearly too evolved for driving.

Sheldon: Well, those are indicators that I'm farther along the evolutionary scale than the average human.
Leonard: No kidding.
Sheldon: Well, no, no, I'm not going to go so far as to say that I represent a distinct new stage in humankind. You know, a Homo Novus, if you will. No, that's for anthropologists to decide. But I am convinced that the reason I cannot master the plebeian task of driving is because I'm not meant to.

Howard: Sheldon, don't take this the wrong way, but, you're insane.
Leonard: That may well be, but the fact is it wouldn't kill us to meet some new people.
Sheldon: For the record, it could kill us to meet new people. They could be murderers or the carriers of unusual pathogens. And I'm not insane, my mother had me tested.

Sheldon: Hey! Look I found my missing neutrino.
Howard: Oh, great! We can take it off the milk carton.

Sheldon: In Papua New Guinea, there's a tribe when a hunter flaunts his success to the rest of the village, they kill him and drive away evil spirits with a drum made of his skin. Superstitious nonsense, of course, but one can see their point.

Raj: They're going to digitally add a supernova they say its the perfect metaphor for my incandescent talent.
Sheldon: Yes, a giant ball of gas that collapses on itself.

Sheldon: Hot air blowers are incubators and spewers of bacteria and pestilence. Frankly, it would be more hygienic if they just had a plague infested gibbon sneeze my hands dry.

Sheldon: Excuse me. Thirty what, under thirty what, to watch what?
Raj: Thirty visionaries under thirty years of age to watch as they challenge the preconceptions of their field.
Sheldon: If I had a million guesses, I never would have gotten that.

Sheldon: How will Raj ever reach true greatness if his friends lower the bar for him? When I was eleven, my sister bought our father a "world's greatest dad" coffee mug, and frankly the man coasted until the day he died.

Sheldon: I wanted a griffin.
Leonard: A griffin.
Sheldon: Yes, half eagle, half lion.
Leonard: And mythological.
Sheldon: Irrelevant. See, I was studying recombinant DNA technology and I was confident I could create one. But my parents were unwilling to secure the necessary eagle eggs and lion semen. Course my sister got swimming lessons when she wanted them.

Sheldon: Danger! Danger!

Sheldon: I'm surprised you struck out with Penny. Apparently she's a big ol' five.

Leonard: Wanna catch me up?
Sheldon: Well, let's see. She attempted to open her apartment with her car key because her face is overly Midwestern. She hasn't had sex in 6 months, and she ate a fly.
Leonard: Uh-huh. Seriously, 6 months?

Sheldon: Level 3 and she thinks she's rich. What a noob!