Penny: Wait, wait, just to be clear, when you guys say spa, does that mean the same thing as when regular people say it?
Leonard: Pretty much. Except we keep our shirts on in the sauna.

Penny: So, Amy, I've been wondering, are you and Sheldon going to be sharing a room?
Amy: No, we discussed it. We decided we didn't want to jeopardize our relationship by getting to know each other too well.
Sheldon: Indeed. Nothing sours a friendship more than over-familiarity with someone's toilet routine.

Penny: Hey, can I stay here tonight?
Leonard: Shh, Sheldon's asleep. What's going on?
Penny: Well, Howard's a complete and total ass, Bernadette's in my bed, and no matter how much you stroke Amy's hair, she bites.

Penny: Sweetie, let me put this in a way you'll understand. From the waist down, my shields are up.

Penny: Hey. So you guys ready to order?
Sheldon: Since we come in every Tuesday night at six o'clock and order the same exact thing, and it's now 6:08, I believe your question not only answers itself, but also stands alongside such other nonsensical queries as "Who let the dogs out?" and, uh, "How are they hanging?"

Amy: Penny, a moment? Do you have plans this weekend?
Penny: Oh, gee, Amy, I'm sorry. I'm actually pretty busy this weekend.
Sheldon: Probably serving food that was ordered today.

Amy: Shame. Since you're my best friend, I thought it would be a good bonding opportunity.
Penny: I'm your best friend?
Amy: Don't you read my blog?
Penny: Oh, don't feel bad. I never read Leonard's, and I used to sleep with him.

Amy: Do you know anybody else who would appreciate an all-expense-paid spa weekend at a four-star resort in Big Sur?
Penny: No, I really - Im sorry, free what? Sorry, what, what?
Leonard: I think her weekend just opened up.

Penny: You know, it is going to be difficult, but I'm going to cancel my plans so I can do this for my bestie.
Amy: Please don't touch my breasts.
Penny: I- I wasn't going to.
Amy: All right. I just want to establish boundaries.

Sheldon: Good morning. If I could have everyone's attention, please? I know we're all eager to get on the road to Big Sur, so if we focus, I'm sure we can get through this orientation in under a half an hour. Then it's just Q&A, quiz, safety drills, pose for commemorative group photo, and we're off.
Leonard: (To Penny) Don't worry. Just sit next to me during the quiz, and you can copy my answers.

Penny: Who elected you Road Trip God?
Sheldon: Leonard...
Leonard: It was a late-night vote. We were all exhausted and he was threatening to filibuster. It's not technically Road Trip God, it's Travel Supervisor.
Sheldon: Although Road Trip God does have a certain ring to it.

Penny: I can't believe you let him kick me out of the car.
Howard: What could we do? He's the Travel Supervisor.

Howard: Hey, Bernie?
Bernadette: Yeah?
Howard: Please tell me he's your gay cousin.
Bernadette: No. He was one of my professors in college.
Howard: Oh! That's a relief.
Bernadette: Then we went out for a year.

Howard: That green bag is Dr. Cooper's. Here's an extra five. Make him wait.

Howard: I'm just thinking. If you had sex with that guy, I mean, there's nothing I can do here that will make any kind of ... impact.